Your Memory Matters (www.yourmemorymatters.com) is a website for those with questions about early memory loss.

Oxidative stress is an early event in neuronal death that is linked to memory loss.

Elevated plasma homocysteine is correlated with neuronal cell death. Loss of neurons is related to loss of acetylcholine, an important neurotransmitter for memory.

Learn how L-methylfolate and methylcobalamin aid in the synthesis of the main memory neurotransmitter, acetylcholine.

L-Methylfolate is the biologically active form of folate, and the only form of folate that is able to cross the blood-brain barrier and be immediately available to the brain.

Methylcobalamin (Methyl-B12) is the principal form of circulating vitamin B12.

N-acetylcysteine (NAC) is a precursor to glutathione (GSH), one of the body's most potent natural antioxidants.

When elderly patients suffering from memory impairment have their dietary need for folate met, their memory performance improves.1

  1. Bottiglieri, T, Progress in Neuro-Psychopharmacology & Biological Psychiatry 29 (2005) 1103-1112
  2. Durga J et al. Effect of a 3 year folic acid supplementation on cognitive function in older adults in the FACIT trial; a randomized, double blind, controlled trial. The Lancet 2007;369:208-216.